Science Links
Human Studies
EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE "OLD" CHROMATIN
Effect of short peptides on neuronal differentiation of stem cells
Identification of Peptide AEDG in the Polypeptide Complex of the Pineal Gland
[Peptides and CCL11 and HMGB1 as molecular markers of aging: literature review and own data]
[Genome instability in pulmonary tuberculosis before and after treatment]
Short cell-penetrating peptides: a model of interactions with gene promoter sites
[Peptide Ala-Glu-Asp-Gly and interferon gamma: their role in immune response during aging]
[Morphofunctional and molecular bases of pineal gland aging]
[Characteristics of the pineal gland and thymus relationship in aging]
[Influence of peptides from pineal gland on thymus function at aging]
[Biological activity of regulatory peptides in model experiments in vitro]
Anti-aging peptide bioregulators induce reactivation of chromatin
Peptide promotes overcoming of the division limit in human somatic cell
Peptide Epitalon activates chromatin at the old age
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Effects of peptides on proliferative activity of retinal and pigmented epithelial cells
Retinoprotective effect of Epithalon in campbell rats of various ages
The role of pineal gland in breast cancer development
Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa
Non-Human Studies
Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro
Peptides (Epigenetic Regulators) in the Structure of Rodents with a Long and Short Lifespan
Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro
[Short peptides stimulate skin cell regeneration during ageing]
Molecular cellular mechanisms of peptide regulation of melatonin synthesis in pinealocyte culture
Effect of short peptides on expression of signaling molecules in organotypic pineal cell culture
Peptidegic stimulation of differentiation of pineal immune cells
Melting of DNA double strand after binding to geroprotective tetrapeptide
[Investigation of antihypoxic properties of short peptides]
[Effect of pineal gland peptides on morphofunctional structure of the pancreas in ageing]
Effects of bioactive tetrapeptides on free-radical processes
Effects of intranasal administration of epitalon on neuron activity in the rat neocortex
Antioxidant properties of geroprotective peptides of the pineal gland
[Intranasal epitalon infusion modulates neuronal activity in the rat neocortex]
Interleukin-2 concentration in hypothalamic structures of rats receiving peptides during mild stress
[Effects of melatonin and epitalone on antioxidant system of rats depends on light conditions]
Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice
DNA double-helix binds regulatory peptides similarly to transcription factors
Effect of melatonin and tetrapeptide on gene expression in mouse brain
[The influence of substances revealing geroprotective of spontaneous carcinogenesis in mice]
Peptide correction of age-related hormonal dysfunction of the pancreas in monkeys
Stressors and antistressors: how do they influence life span in HER-2/neu transgenic mice?
[Effect of epitalon on the immunity and hemostasis in hypophysectomized chicken and old hens]
[Peptide correction of age-related pineal disturbances in monkeys]
Effect of regulatory peptides on gene transcription
Epitalon influences pineal secretion in stress-exposed rats in the daytime
Effects of pineal-gland peptides on the electric activity of pinealocytes in rats
In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes
Effects of epithalon on activities gastrointestinal enzymes in young and old rats
Effect of epithalon on the incidence of chromosome aberrations in senescence-accelerated mice
[Effect of Epitalon and Vilon treatment on mammary carcinogenesis in transgenic erbB-2/NEU mice]
[Tissue-specific action of peptides in tissue culture of rats of various ages]
[Effect of vilon and epithalone on induction and growth of induced bladder neoplasms in rats]
[Effect of epithalone on growth kinetics and functional morphology of M-1 sarcoma]
Regulatory effect of Epithalon on production of melatonin and cortisol in old monkeys
Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys
[Effect of pineal peptides on neuroendocrine system after pinealectomy]
Reparative effect of epithalon on pineal gland ultrastructure in gamma-irradiated rats
Peptide bioregulators inhibit apoptosis
Regulating effect of epithalone on gastric endocrine cells in pinealectomized rats
[Effect of pineal peptide on parameters of the biological age and life span in mice]
Effect of the Ala-Glu-Asp-Gly peptide on lifespan in Drosophila melanogaster
Effect of epitalon on the lifespan increase in Drosophila melanogaster